Application
Western blot analysis of GDF11 (arrow) using rabbit polyclonal GDF11 Antibody (R47) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GDF11 gene (Lane 2) (Origene Technologies).Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with GDF11 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | GDF11 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BMP11 |
|---|---|
| Alternative Names | GDF11 BMP11 Growth/differentiation factor 11 Bone morphogenetic protein 11 |
| Molecular Weight(MW) | 45091 Da |
| Function | Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern |
| Tissue Specificity | This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40~69 amino acids from the N-terminal region of human GDF11. |
| Cellular Localization | Secreted (Probable). |
| Entrez Gene | 10220 |
|---|
Application
Western blot analysis of GDF11 (arrow) using rabbit polyclonal GDF11 Antibody (R47) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GDF11 gene (Lane 2) (Origene Technologies).
Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with GDF11 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
