Application
GDF9 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GDF9 antibody detected the GDF9 protein (arrow).Application
GDF9 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GDF9 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GDF9 Growth/differentiation factor 9 |
|---|---|
| Molecular Weight(MW) | 51444 Da |
| Function | Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B It suppresses FST and FSTL3 production in granulosa-lutein cells |
| Tissue Specificity | Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level) |
| Cellular Localization | Secreted (By similarity). |
| Entrez Gene | 2661 |
|---|---|
| Nucleotide Accession | NP_005251.1 |
Application
GDF9 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GDF9 antibody detected the GDF9 protein (arrow).
Application
GDF9 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
