Application
A. Western blot analysis on human plasma using anti-Gelsolin RabMAb (Cat. #AJ1319b), dilution 1:50,000.Application
B. Paraffin-embedded human colon tissue stained with anti-Gelsolin RabMAb. Note positive staining of vessels (Cat. #AJ1319b).| Product Name | Gelsolin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR1941Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:5000~20000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GSN Gelsolin Brevin AGEL |
|---|---|
| Molecular Weight(MW) | 85698 Da |
| Function | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis |
| Tissue Specificity | Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells |
| Cellular Localization | Isoform 2: Cytoplasm, cytoskeleton. |
| Entrez Gene | 2934 |
|---|
Application
A. Western blot analysis on human plasma using anti-Gelsolin RabMAb (Cat. #AJ1319b), dilution 1:50,000.
Application
B. Paraffin-embedded human colon tissue stained with anti-Gelsolin RabMAb. Note positive staining of vessels (Cat. #AJ1319b).| Application Notes | WB:1:5000~20000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
