Application
Western blot analysis of GEN1 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). GEN1 (arrow) was detected using the purified Pab;Application
Western blot analysis of GEN1 Antibody (N-term) in mouse liver tissue lysates (35ug/lane). GEN1 (arrow) was detected using the purified Pab.| Product Name | GEN1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GEN1 Flap endonuclease GEN homolog 1 |
|---|---|
| Molecular Weight(MW) | 102884 Da |
| Function | Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation |
| Tissue Specificity | This GEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67~97 amino acids from the N-terminal region of human GEN1. |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 348654 |
|---|
Application
Western blot analysis of GEN1 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). GEN1 (arrow) was detected using the purified Pab;
Application
Western blot analysis of GEN1 Antibody (N-term) in mouse liver tissue lysates (35ug/lane). GEN1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
