Application
GFRA4 Antibody (Center) western blot analysis in HL-60,ZR-75-1,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GFRA4 antibody detected the GFRA4 protein (arrow).| Product Name | GFRA4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GFRA4 GDNF family receptor alpha-4 Persephin receptor |
|---|---|
| Molecular Weight(MW) | 31670 Da |
| Function | Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla |
| Tissue Specificity | Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands |
| Cellular Localization | Isoform GFRalpha4a: Cell membrane; Lipid- anchor, GPI-anchor Isoform GFRalpha4c: Secreted. |
| Entrez Gene | 64096 |
|---|---|
| Nucleotide Accession | NP_665705.1 NP_071422.1 |
Application
GFRA4 Antibody (Center) western blot analysis in HL-60,ZR-75-1,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GFRA4 antibody detected the GFRA4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
