Application
GGT1 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GGT1 antibody detected the GGT1 protein (arrow).Application
GGT1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the GGT1 antibody detected the GGT1 protein (arrow).| Product Name | GGT1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GGT |
|---|---|
| Alternative Names | GGT1 GGT Gamma-glutamyltranspeptidase 1 Gamma-glutamyltransferase 1 Glutathione hydrolase 1 Leukotriene-C4 hydrolase CD_antigen=CD224 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain |
| Molecular Weight(MW) | 61410 Da |
| Function | Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive |
| Tissue Specificity | Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Entrez Gene | 2678 |
|---|---|
| Nucleotide Accession | NP_038347.2 |
Application
GGT1 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GGT1 antibody detected the GGT1 protein (arrow).
Application
GGT1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the GGT1 antibody detected the GGT1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
