Application
Western blot analysis of GIMAP5 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). GIMAP5 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human spleen reacted with GIMAP5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Flow cytometric analysis of MDA-231 cells using GIMAP5 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | GIMAP5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IAN4L1, IAN5, IMAP3 |
|---|---|
| Alternative Names | GIMAP5 IAN4L1 IAN5 IMAP3 GTPase IMAP family member 5 Immunity-associated nucleotide 4-like 1 protein Immunity-associated nucleotide 5 protein Immunity-associated protein 3 |
| Molecular Weight(MW) | 34846 Da |
| Function | Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity) |
| Tissue Specificity | Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T- cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms |
| Cellular Localization | Mitochondrion outer membrane; Single-pass type IV membrane protein (By similarity). Lysosome |
| Entrez Gene | 55340 |
|---|
Application
Western blot analysis of GIMAP5 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). GIMAP5 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human spleen reacted with GIMAP5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Flow cytometric analysis of MDA-231 cells using GIMAP5 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
