Application
Western blot analysis of anti-GPC6 Pab in K562 cell line lysates (35ug/lane). GPC6(arrow) was detected using the purified Pab (1:60 dilution).| Product Name | Glypican 6 (GPC6) Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPC6; Glypican-6; Secreted glypican-6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GPC6 Glypican-6 Secreted glypican-6 |
|---|---|
| Molecular Weight(MW) | 62736 Da |
| Function | Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity) Enhances migration and invasion of cancer cells through WNT5A signaling |
| Tissue Specificity | Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes. Detected in breast cancer cells (at protein level) |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side (By similarity) |
| Entrez Gene | 10082 |
|---|
Application
Western blot analysis of anti-GPC6 Pab in K562 cell line lysates (35ug/lane). GPC6(arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
