Application
GM2A Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).Application
GM2A Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).| Product Name | GM2A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GM2A Ganglioside GM2 activator Cerebroside sulfate activator protein GM2-AP Shingolipid activator protein 3 Ganglioside GM2 activator isoform short |
|---|---|
| Molecular Weight(MW) | 20838 Da |
| Function | The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3 |
| Tissue Specificity | This GM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-62 amino acids from the N-terminal region of human GM2A. |
| Cellular Localization | Lysosome. |
| Entrez Gene | 2760 |
|---|---|
| Nucleotide Accession | NP_000396.2 |
Application
GM2A Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).
Application
GM2A Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the GM2A antibody detected the GM2A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
