Application
Western blot analysis of GMNN Antibody (Center Y111) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.Application
GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GMNN Antibody (Center Y111) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GMNN; Geminin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GMNN Geminin |
|---|---|
| Molecular Weight(MW) | 23565 Da |
| Function | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle |
| Tissue Specificity | This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-134 amino acids from the Central region of human GMNN. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus |
| Entrez Gene | 51053 |
|---|
Application
Western blot analysis of GMNN Antibody (Center Y111) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.
Application
GMNN Antibody (Center Y111) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
