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GNAQ Antibody (N-term)

Catalog Number:OM234193
OM234193
Discount Price
OM234193-100ul
1~2 Week
100ul
OM234193-50ul
50ul
OM234193-20ul
20ul
1~2 Week
Product Profile
Product Name GNAQ Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias GNAQ; GAQ; Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding protein alpha-q
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms GAQ
Alternative Names GNAQ
GAQ
Guanine nucleotide-binding protein G(q) subunit alpha
Guanine nucleotide-binding protein alpha-q
Molecular Weight(MW) 42142 Da
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity)
Tissue Specificity Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level)
Cellular Localization Nucleus (By similarity). Membrane (By similarity). Nucleus membrane (By similarity). Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity)
Database Links
Entrez Gene 2776
Nucleotide Accession NP_002063.2
Application

Application

GNAQ Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the GNAQ antibody detected the GNAQ protein (arrow).

Application

Western blot analysis of GNAQ (arrow) using rabbit polyclonal GNAQ Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNAQ gene.
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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