GNAS; GNAS1; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Adenylate cyclase-stimulating G alpha protein; Extra large alphas protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
GNAS1
Alternative Names
GNAS GNAS1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Adenylate cyclase-stimulating G alpha protein Extra large alphas protein
Molecular Weight(MW)
111025 Da
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity)
Tissue Specificity
This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646~676 amino acids from the Center region of human GNAS.
Cellular Localization
Cell membrane; Peripheral membrane protein (By similarity)
Western blot analysis of GNAS Antibody (Center) in Ramos cell line lysates (35ug/lane). GNAS (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.