Application
GP6 Antibody (C-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the GP6 antibody detected the GP6 protein (arrow).Application
GP6 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | GP6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GP6; Platelet glycoprotein VI; Glycoprotein 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GP6 Platelet glycoprotein VI Glycoprotein 6 |
|---|---|
| Molecular Weight(MW) | 36866 Da |
| Function | Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2 |
| Tissue Specificity | Megakaryocytes and platelets. |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass membrane protein |
| Entrez Gene | 51206 |
|---|---|
| Nucleotide Accession | NP_057447.4 |
Application
GP6 Antibody (C-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the GP6 antibody detected the GP6 protein (arrow).
Application
GP6 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
