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GPD1L Antibody (N-term)

Catalog Number:OM234310
OM234310
Discount Price
OM234310-100ul
1~2 Week
100ul
OM234310-50ul
50ul
OM234310-20ul
20ul
1~2 Week
Product Profile
Product Name GPD1L Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias GPD1L; KIAA0089; Glycerol-3-phosphate dehydrogenase 1-like protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KIAA0089
Alternative Names GPD1L
KIAA0089
Glycerol-3-phosphate dehydrogenase 1-like protein
Molecular Weight(MW) 38419 Da
Function Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L
Tissue Specificity Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs
Cellular Localization Cytoplasm. Note=Localized to the region of the plasma membrane
Database Links
Entrez Gene 23171
Nucleotide Accession NP_055956.1
Application

Application

GPD1L Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GPD1L antibody detected the GPD1L protein (arrow).

Application

GPD1L Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the GPD1L antibody detected the GPD1L protein (arrow).

Application

GPD1L antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPD1L antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

GPD1L Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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