Application
GPR109B Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the GPR109B antibody detected the GPR109B protein (arrow).| Product Name | GPR109B Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HCAR3; GPR109B; HCA3; HM74B; NIACR2; Hydroxycarboxylic acid receptor 3; Nicotinic acid receptor 2; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Niacin receptor 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GPR109B HCA3 HM74B NIACR2 |
|---|---|
| Alternative Names | HCAR3 GPR109B HCA3 HM74B NIACR2 Hydroxycarboxylic acid receptor 3 Nicotinic acid receptor 2 G-protein coupled receptor 109B G-protein coupled receptor HM74 G-protein coupled receptor HM74B Niacin receptor 2 |
| Molecular Weight(MW) | 44496 Da |
| Function | Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet |
| Tissue Specificity | Expression largely restricted to adipose tissue and spleen |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 8843 |
|---|---|
| Nucleotide Accession | NP_006009.2 |
Application
GPR109B Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the GPR109B antibody detected the GPR109B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
