Application
Western blot analysis of GPR17 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). GPR17 (arrow) was detected using the purified Pab.Application
GPR17 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPR17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
GPR17 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | GPR17 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; G-protein coupled receptor 17; P2Y-like receptor; R12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GPR17 Uracil nucleotide/cysteinyl leukotriene receptor G-protein coupled receptor 17 P2Y-like receptor R12 |
|---|---|
| Molecular Weight(MW) | 40989 Da |
| Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia |
| Tissue Specificity | Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 2840 |
|---|
Application
Western blot analysis of GPR17 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). GPR17 (arrow) was detected using the purified Pab.
Application
GPR17 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPR17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
GPR17 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
