Application
GPR84 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GPR84 antibody detected the GPR84 protein (arrow).| Product Name | GPR84 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPR84; EX33; G-protein coupled receptor 84; Inflammation-related G-protein coupled receptor EX33 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EX33 |
|---|---|
| Alternative Names | GPR84 EX33 G-protein coupled receptor 84 Inflammation-related G-protein coupled receptor EX33 |
| Molecular Weight(MW) | 43705 Da |
| Function | Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system |
| Tissue Specificity | Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 53831 |
|---|---|
| Nucleotide Accession | NP_065103.1 |
Application
GPR84 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GPR84 antibody detected the GPR84 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
