Application
Western blot analysis of anti-GTF2H2 Antibody (N-term) in K562 cell line lysates (35ug/lane). GTF2H2(arrow) was detected using the purified Pab.| Product Name | GTF2H2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GTF2H2; BTF2P44; General transcription factor IIH subunit 2; Basic transcription factor 2 44 kDa subunit; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BTF2P44 |
|---|---|
| Alternative Names | GTF2H2 BTF2P44 General transcription factor IIH subunit 2 Basic transcription factor 2 44 kDa subunit General transcription factor IIH polypeptide 2 TFIIH basal transcription factor complex p44 subunit |
| Molecular Weight(MW) | 44419 Da |
| Function | Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C- terminus is required for a successful escape of RNAP II form the promoter |
| Tissue Specificity | Widely expressed, with higher expression in skeletal muscle |
| Cellular Localization | Nucleus. |
| Entrez Gene | 2966 |
|---|
Application
Western blot analysis of anti-GTF2H2 Antibody (N-term) in K562 cell line lysates (35ug/lane). GTF2H2(arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
