Application
GUCY2D Antibody (Center) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the GUCY2D antibody detected the GUCY2D protein (arrow).Application
GUCY2D Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GUCY2D Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
GUCY2D Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | GUCY2D Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GUCY2D; CORD6; GUC1A4; GUC2D; RETGC; RETGC1; Retinal guanylyl cyclase 1; Guanylate cyclase 2D, retinal; Rod outer segment membrane guanylate cyclase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CORD6 GUC1A4 GUC2D RETGC RETGC1 |
|---|---|
| Alternative Names | GUCY2D CORD6 GUC1A4 GUC2D RETGC RETGC1 Retinal guanylyl cyclase 1 Guanylate cyclase 2D retinal Rod outer segment membrane guanylate cyclase |
| Molecular Weight(MW) | 120059 Da |
| Function | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction |
| Tissue Specificity | Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 3000 |
|---|---|
| Nucleotide Accession | NP_000171.1 |
Application
GUCY2D Antibody (Center) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the GUCY2D antibody detected the GUCY2D protein (arrow).
Application
GUCY2D Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GUCY2D Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
GUCY2D Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
