Application
GZMA Antibody (Center K128) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GZMA antibody detected the GZMA protein (arrow).Application
GZMA Antibody (Center K128) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GZMA Antibody (Center K128) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GZMA Antibody (Center K128) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GZMA; CTLA3; HFSP; Granzyme A; CTL tryptase; Cytotoxic T-lymphocyte proteinase 1; Fragmentin-1; Granzyme-1; Hanukkah factor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CTLA3 HFSP |
|---|---|
| Alternative Names | GZMA CTLA3 HFSP Granzyme A CTL tryptase Cytotoxic T-lymphocyte proteinase 1 Fragmentin-1 Granzyme-1 Hanukkah factor |
| Molecular Weight(MW) | 28999 Da |
| Function | This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity Involved in apoptosis |
| Tissue Specificity | This GZMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-152 amino acids from the Central region of human GZMA. |
| Cellular Localization | Isoform alpha: Secreted. Cytoplasmic granule |
Application
GZMA Antibody (Center K128) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GZMA antibody detected the GZMA protein (arrow).
Application
GZMA Antibody (Center K128) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GZMA Antibody (Center K128) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
