Application
H1FOO Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the H1FOO antibody detected the H1FOO protein (arrow).| Product Name | H1FOO Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | H1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | H1OO OSH1 |
|---|---|
| Alternative Names | H1FOO H1OO OSH1 Histone H1oo Oocyte-specific histone H1 Oocyte-specific linker histone H1 |
| Molecular Weight(MW) | 35813 Da |
| Function | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity) |
| Tissue Specificity | Oocyte-specific. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Chromosome (By similarity) |
| Entrez Gene | 132243 |
|---|---|
| Nucleotide Accession | NP_722575.1 |
Application
H1FOO Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the H1FOO antibody detected the H1FOO protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
