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H2A1H Antibody (N-term)

Catalog Number:OM234681
OM234681
Discount Price
OM234681-100ul
1~2 Week
100ul
OM234681-50ul
50ul
OM234681-20ul
20ul
1~2 Week
Product Profile
Product Name H2A1H Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias HIST1H2AH; HIST1H2AI; Histone H2A type 1-H; Histone H2A/s
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms HIST1H2AI
Alternative Names HIST1H2AH
HIST1H2AI
Histone H2A type 1-H
Histone H2A/s
Molecular Weight(MW) 13906 Da
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Tissue Specificity This H2A1H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human H2A1H.
Cellular Localization Nucleus. Chromosome.
Database Links
Entrez Gene 85235
Application

Application

Western blot analysis of H2A1H Antibody (N-term) in K562 cell line lysates (35ug/lane).H2A1H (arrow) was detected using the purified Pab.

Application

H2A1H Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the H2A1H Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

H2A1H Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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