Application
H2AFY2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the H2AFY2 antibody detected the H2AFY2 protein (arrow).Application
H2AFY2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | H2AFY2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | H2AFY2; MACROH2A2; Core histone macro-H2A.2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MACROH2A2 |
|---|---|
| Alternative Names | H2AFY2 MACROH2A2 Core histone macro-H2A.2 |
| Molecular Weight(MW) | 40058 Da |
| Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation |
| Tissue Specificity | This H2AFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human H2AFY2. |
| Cellular Localization | Nucleus. Chromosome. Note=Enriched in inactive X chromosome chromatin and in senescence-associated heterochromatin |
| Entrez Gene | 55506 |
|---|---|
| Nucleotide Accession | NP_061119.1 |
Application
H2AFY2 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the H2AFY2 antibody detected the H2AFY2 protein (arrow).
Application
H2AFY2 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
