Application
HAT1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HAT1 antibody detected the HAT1 protein (arrow).Application
Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.| Product Name | HAT1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HAT1; KAT1; Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KAT1 |
|---|---|
| Alternative Names | HAT1 KAT1 Histone acetyltransferase type B catalytic subunit Histone acetyltransferase 1 |
| Molecular Weight(MW) | 49513 Da |
| Function | Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage |
| Tissue Specificity | This HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human HAT1. |
| Cellular Localization | Isoform A: Nucleus matrix. |
| Entrez Gene | 8520 |
|---|---|
| Nucleotide Accession | NP_003633.1 |
Application
HAT1 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HAT1 antibody detected the HAT1 protein (arrow).
Application
Western blot analysis of HAT1 (arrow) using rabbit polyclonal HAT1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HAT1 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
