Application
Western blot analysis of HDAC10(arrow) using rabbit polyclonal HDAC10 antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HDAC10 gene (Lane 2) (Origene Technologies).Application
HDAC10 Antibody (R623) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HDAC10 antibody detected the HDAC10 protein (arrow).| Product Name | HDAC10 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HDAC10; Histone deacetylase 10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HDAC10 Histone deacetylase 10 |
|---|---|
| Molecular Weight(MW) | 71445 Da |
| Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes |
| Tissue Specificity | Ubiquitous. High expression in liver, spleen, pancreas and kidney |
| Cellular Localization | Cytoplasm. Nucleus. Note=Excluded from the nucleoli |
| Entrez Gene | 83933 |
|---|
Application
Western blot analysis of HDAC10(arrow) using rabbit polyclonal HDAC10 antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HDAC10 gene (Lane 2) (Origene Technologies).
Application
HDAC10 Antibody (R623) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the HDAC10 antibody detected the HDAC10 protein (arrow).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
