Application
The anti-HDAC11 Pab is used in Western blot to detect HDAC11 in mouse brain tissue lysate.Application
Purified rabbit anti-HDAC11 antibody (C-term) was used in immunohistochemistry on Breast Carcinoma.Application
Formalin-fixed and paraffin-embedded human testicle tumor tissue reacted with HDAC11 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | HDAC11 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HDAC11; Histone deacetylase 11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HDAC11 Histone deacetylase 11 |
|---|---|
| Molecular Weight(MW) | 39183 Da |
| Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes |
| Tissue Specificity | Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis |
| Cellular Localization | Nucleus. Note=Predominantly nuclear. |
| Entrez Gene | 79885 |
|---|
Application
The anti-HDAC11 Pab is used in Western blot to detect HDAC11 in mouse brain tissue lysate.
Application
Purified rabbit anti-HDAC11 antibody (C-term) was used in immunohistochemistry on Breast Carcinoma.
Application
Formalin-fixed and paraffin-embedded human testicle tumor tissue reacted with HDAC11 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
