Application
HECTD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).| Product Name | HECTD3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HECTD3; E3 ubiquitin-protein ligase HECTD3; HECT domain-containing protein 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HECTD3 E3 ubiquitin-protein ligase HECTD3 HECT domain-containing protein 3 |
|---|---|
| Molecular Weight(MW) | 97113 Da |
| Function | E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity) |
| Tissue Specificity | This HECTD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 739-769 amino acids from the C-terminal region of human HECTD3. |
| Cellular Localization | Cytoplasm, perinuclear region (By similarity) |
| Entrez Gene | 79654 |
|---|---|
| Nucleotide Accession | NP_078878.3 |
Application
HECTD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
