Application
Western blot analysis of HES6 Antibody (N-term) in MCF-7 cell line lysates (35ug/lane). HES6 (arrow) was detected using the purified Pab.| Product Name | HES6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HES6; BHLHB41; Transcription cofactor HES-6; C-HAIRY1; Class B basic helix-loop-helix protein 41; Hairy and enhancer of split 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHB41 |
|---|---|
| Alternative Names | HES6 BHLHB41 Transcription cofactor HES-6 C-HAIRY1 Class B basic helix-loop-helix protein 41 Hairy and enhancer of split 6 |
| Molecular Weight(MW) | 24129 Da |
| Function | Does not bind DNA itself but suppresses both HES1- mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence Promotes cell differentiation (By similarity) |
| Tissue Specificity | This HES6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13~42 amino acids from the N-terminal region of human HES6. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 55502 |
|---|
Application
Western blot analysis of HES6 Antibody (N-term) in MCF-7 cell line lysates (35ug/lane). HES6 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
