HERPUD1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HERPUD1 antibody detected the HERPUD1 protein (arrow).
HERPUD1; HERP; KIAA0025; MIF1; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; Methyl methanesulfonate (MMF)-inducible fragment protein 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
HERP KIAA0025 MIF1
Alternative Names
HERPUD1 HERP KIAA0025 MIF1 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein Methyl methanesulfonate (MMF)-inducible fragment protein 1
Molecular Weight(MW)
43720 Da
Function
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation
Tissue Specificity
Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein
HERPUD1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HERPUD1 antibody detected the HERPUD1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.