Application
Western blot analysis of HFE2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). HFE2 (arrow) was detected using the purified Pab.Application
HFE2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | HFE2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HFE2; HJV; RGMC; Hemojuvelin; Hemochromatosis type 2 protein; RGM domain family member C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HJV RGMC |
|---|---|
| Alternative Names | HFE2 HJV RGMC Hemojuvelin Hemochromatosis type 2 protein RGM domain family member C |
| Molecular Weight(MW) | 45080 Da |
| Function | Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin |
| Tissue Specificity | Adult and fetal liver, heart, and skeletal muscle |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor (By similarity) |
| Entrez Gene | 148738 |
|---|
Application
Western blot analysis of HFE2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). HFE2 (arrow) was detected using the purified Pab.
Application
HFE2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
