HILPDA C7orf68 HIG2 Hypoxia-inducible lipid droplet-associated protein Hypoxia-inducible gene 2 protein
Molecular Weight(MW)
6950 Da
Function
Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation
Tissue Specificity
Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level)
Cellular Localization
Lipid droplet. Secreted. Membrane; Single- pass membrane protein (Potential)
Western blot analysis of HIG2 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). HIG2 (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.