HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HIST1H2BH/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BH/HIST1H2BK/HIST3H2BB protein (arrow).
HIST1H2BH H2BFJ Histone H2B type 1-H Histone H2B.j
Molecular Weight(MW)
13892 Da
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Tissue Specificity
This HIST1H2BH/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the Central region of human HIST1H2BH/HIST1H2BK/HIST3H2BB.
HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HIST1H2BH/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BH/HIST1H2BK/HIST3H2BB protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.