Application
Western blot analysis of HMBS (arrow) using rabbit polyclonal HMBS Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HMBS gene.Application
HMBS Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMBS Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | HMBS Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PBGD, UPS |
|---|---|
| Alternative Names | HMBS PBGD UPS Porphobilinogen deaminase Hydroxymethylbilane synthase Pre-uroporphyrinogen synthase |
| Molecular Weight(MW) | 39330 Da |
| Function | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps |
| Tissue Specificity | Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells |
| Cellular Localization | Cytoplasm (Probable). |
| Entrez Gene | 3145 |
|---|---|
| Nucleotide Accession | NP_001019553.1 NP_000181.2 |
Application
Western blot analysis of HMBS (arrow) using rabbit polyclonal HMBS Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HMBS gene.
Application
HMBS Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMBS Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
