Application
HMMR Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HMMR antibody detected the HMMR protein (arrow).Application
HMMR Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMMR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
HMMR Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | HMMR Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IHABP, RHAMM |
|---|---|
| Alternative Names | HMMR IHABP RHAMM Hyaluronan mediated motility receptor Intracellular hyaluronic acid-binding protein Receptor for hyaluronan-mediated motility CD_antigen=CD168 |
| Molecular Weight(MW) | 84100 Da |
| Function | Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity |
| Tissue Specificity | Expressed in breast cancer cell lines and in normal breast tissue |
| Cellular Localization | Cell surface. Cytoplasm (By similarity). |
| Entrez Gene | 3161 |
|---|---|
| Nucleotide Accession | NP_036616.2 |
Application
HMMR Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HMMR antibody detected the HMMR protein (arrow).
Application
HMMR Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMMR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
HMMR Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
