Application
HNRPDL Antibody (Center) western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).This demonstrates the HNRPDL antibody detected the HNRPDL protein (arrow).| Product Name | HNRPDL Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HNRPDL; JKTBP; Heterogeneous nuclear ribonucleoprotein D-like; AU-rich element RNA-binding factor; JKT41-binding protein; Protein laAUF1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | JKTBP |
|---|---|
| Alternative Names | HNRPDL JKTBP Heterogeneous nuclear ribonucleoprotein D-like AU-rich element RNA-binding factor JKT41-binding protein Protein laAUF1 |
| Molecular Weight(MW) | 46438 Da |
| Function | Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity) Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes Expressed in myeloid leukemia, gastric adenocarcinoma, cervical carcinoma, hepatoma, fibrosarcoma, colon adenocarcinoma, epidermoid carcinoma, osteosarcoma and urinary bladder carcinoma cells |
| Cellular Localization | Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner |
| Entrez Gene | 9987 |
|---|---|
| Nucleotide Accession | NP_112740.1 |
Application
HNRPDL Antibody (Center) western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).This demonstrates the HNRPDL antibody detected the HNRPDL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
