Application
HOOK1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HOOK1 antibody detected the HOOK1 protein (arrow).| Product Name | HOOK1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HOOK1; Protein Hook homolog 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HOOK1 Protein Hook homolog 1 |
|---|---|
| Molecular Weight(MW) | 84648 Da |
| Function | Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex) The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) |
| Tissue Specificity | This HOOK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-431 amino acids from the Central region of human HOOK1. |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Cytoplasm. Note=Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules |
| Entrez Gene | 51361 |
|---|---|
| Nucleotide Accession | NP_056972.1 |
Application
HOOK1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the HOOK1 antibody detected the HOOK1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
