Application
HPSE2 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the HPSE2 antibody detected the HPSE2 protein (arrow).Application
HPSE2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HPSE2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | HPSE2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HPSE2; HPA2; Inactive heparanase-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HPA2 |
|---|---|
| Alternative Names | HPSE2 HPA2 Inactive heparanase-2 |
| Molecular Weight(MW) | 66596 Da |
| Function | Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro) |
| Tissue Specificity | Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 60495 |
|---|---|
| Nucleotide Accession | NP_001159717.1 |
Application
HPSE2 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the HPSE2 antibody detected the HPSE2 protein (arrow).
Application
HPSE2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HPSE2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
