Application
HSD17B8 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the HSD17B8 antibody detected the HSD17B8 protein (arrow).Application
HSD17B8 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | HSD17B8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HSD17B8; FABGL; HKE6; RING2; Estradiol 17-beta-dehydrogenase 8; 17-beta-hydroxysteroid dehydrogenase 8; 3-oxoacyl-[acyl-carrier-protein] reductase; Protein Ke6; Really interesting new gene 2 protein; Testosterone 17-beta-dehydrogenase 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FABGL HKE6 RING2 |
|---|---|
| Alternative Names | HSD17B8 FABGL HKE6 RING2 Estradiol 17-beta-dehydrogenase 8 17-beta-hydroxysteroid dehydrogenase 8 3-oxoacyl-[acyl-carrier-protein] reductase Protein Ke6 Really interesting new gene 2 protein Testosterone 17-beta-dehydrogenase 8 |
| Molecular Weight(MW) | 26974 Da |
| Function | NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria |
| Tissue Specificity | Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed |
| Cellular Localization | Mitochondrion matrix. |
| Entrez Gene | 7923 |
|---|---|
| Nucleotide Accession | NP_055049.1 |
Application
HSD17B8 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the HSD17B8 antibody detected the HSD17B8 protein (arrow).
Application
HSD17B8 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
