HSD3B7; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; Cholest-5-ene-3-beta, 7-alpha-diol 3-beta-dehydrogenase
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
HSD3B7 3 beta-hydroxysteroid dehydrogenase type 7 3 beta-hydroxysteroid dehydrogenase type VII 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase Cholest-5-ene-3-beta 7-alpha-diol 3-beta-dehydrogenase
Molecular Weight(MW)
41016 Da
Function
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates Involved in bile acid synthesis
Tissue Specificity
This HSD3B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-166 amino acids from the Central region of human HSD3B7.
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein
Western blot analysis of HSD3B7 Antibody (Center) in mouse NIH-3T3 cell line lysates (35ug/lane).HSD3B7 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.