Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function
Tissue Specificity
This HSPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409~439 amino acids from the Center region of human HSPCB.
Cellular Localization
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Western blot analysis of HSPCB Antibody (Center) in Jurkat, K562 cell line lysates (35ug/lane). HSPCB (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.