Application
HTR4 Antibody (N-term) western blot analysis in MDA-MB453(lane 1) cell line and mouse liver(lane 2) tissue lysates (35ug/lane).This demonstrates the HTR4 antibody detected the HTR4 protein (arrow).| Product Name | HTR4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HTR4; 5-hydroxytryptamine receptor 4; Serotonin receptor 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | HTR4 5-hydroxytryptamine receptor 4 Serotonin receptor 4 |
|---|---|
| Molecular Weight(MW) | 43761 Da |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase |
| Tissue Specificity | Isoform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli (By similarity) |
| Entrez Gene | 3360 |
|---|---|
| Nucleotide Accession | NP_001035259.1 NP_000861.1 NP_955525.1 NP_001035262.2 |
Application
HTR4 Antibody (N-term) western blot analysis in MDA-MB453(lane 1) cell line and mouse liver(lane 2) tissue lysates (35ug/lane).This demonstrates the HTR4 antibody detected the HTR4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
