ICAM1, Intercellular adhesion molecule 1, Major group rhinovirus receptor
Key Feature
Clonality
Monoclonal
Clone Number
EP1442Y
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:1000~2000 IHC
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
ICAM1 Intercellular adhesion molecule 1 Major group rhinovirus receptor
Molecular Weight(MW)
57825 Da
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation In case of rhinovirus infection acts as a cellular receptor for the virus
Tissue Specificity
A synthetic peptide corresponding to residues near the N-terminus of human ICAM-1 was used as an immunogen.