Application
The anti-ICMT Pab is used in Western blot to detect ICMT in T47D (left) and SK-BR-3 (right) tissue lysate| Product Name | ICMT (C-term) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ICMT; PCCMT; Protein-S-isoprenylcysteine O-methyltransferase; Isoprenylcysteine carboxylmethyltransferase; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PCCMT |
|---|---|
| Alternative Names | ICMT PCCMT Protein-S-isoprenylcysteine O-methyltransferase Isoprenylcysteine carboxylmethyltransferase Prenylated protein carboxyl methyltransferase Prenylcysteine carboxyl methyltransferase |
| Molecular Weight(MW) | 31938 Da |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions Abundant expression seen in the Purkinje cells and pontine neurons |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Entrez Gene | 23463 |
|---|
Application
The anti-ICMT Pab is used in Western blot to detect ICMT in T47D (left) and SK-BR-3 (right) tissue lysate| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
