Application
ICT1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ICT1 antibody detected the ICT1 protein (arrow).| Product Name | ICT1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ICT1;DS1; Peptidyl-tRNA hydrolase ICT1, mitochondrial; Peptidyl-tRNA hydrolase ICT1, mitochondrial; Digestion substraction 1; Peptidyl-tRNA hydrolase ICT1, mitochondrial; Immature colon carcinoma transcript 1 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DS1 |
|---|---|
| Alternative Names | ICT1 DS1 Peptidyl-tRNA hydrolase ICT1 mitochondrial Peptidyl-tRNA hydrolase ICT1 mitochondrial Digestion substraction 1 Peptidyl-tRNA hydrolase ICT1 mitochondrial Immature colon carcinoma transcript 1 protein |
| Molecular Weight(MW) | 23630 Da |
| Function | Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes |
| Tissue Specificity | Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 3396 |
|---|
Application
ICT1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ICT1 antibody detected the ICT1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
