Application
Western blot analysis of IFM2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). IFM2 (arrow) was detected using the purified Pab.Application
IFM2 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IFM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | IFM2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IFITM2; Interferon-induced transmembrane protein 2; Dispanin subfamily A member 2c; Interferon-inducible protein 1-8D |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IFITM2 Interferon-induced transmembrane protein 2 Dispanin subfamily A member 2c Interferon-inducible protein 1-8D |
|---|---|
| Molecular Weight(MW) | 14632 Da |
| Function | IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner |
| Tissue Specificity | This IFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human IFM2. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (Potential) |
| Entrez Gene | 10581 |
|---|
Application
Western blot analysis of IFM2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). IFM2 (arrow) was detected using the purified Pab.
Application
IFM2 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IFM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
