Application
IKBKE Antibody (N41) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IKBKE antibody detected the IKBKE protein (arrow).| Product Name | IKK epsilon (IKKE) Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IKKE, IKKI, KIAA0151 |
|---|---|
| Alternative Names | IKBKE IKKE IKKI KIAA0151 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inducible I kappa-B kinase |
| Molecular Weight(MW) | 80462 Da |
| Function | Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage- induced cell death |
| Tissue Specificity | Highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus, PML body. Note=Targeting to PML nuclear bodies upon DNA damage is TOPORS- dependent |
| Entrez Gene | 9641 |
|---|
Application
IKBKE Antibody (N41) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IKBKE antibody detected the IKBKE protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
