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IL12_2 Antibody (C-term)

Catalog Number:OM235813
OM235813
Discount Price
OM235813-100ul
1~2 Week
100ul
OM235813-50ul
50ul
OM235813-20ul
20ul
1~2 Week
Product Profile
Product Name IL12_2 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names IL12RB2
Interleukin-12 receptor subunit beta-2
Molecular Weight(MW) 97135 Da
Function Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production
Tissue Specificity Isoform 2 is expressed at similar levels in both naive and activated T-cells
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 3595
Nucleotide Accession NP_001550.1
Application

Application

IL12RB2 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the IL12RB2 antibody detected the IL12Cat. #2 protein (arrow).

Application

IL12RB2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsils tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IL12RB2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

IL12RB2 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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