Application
IL17RE Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IL17RE antibody detected the IL17RE protein (arrow).| Product Name | IL17RE (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL17RE; Interleukin-17 receptor E |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IL17RE Interleukin-17 receptor E |
|---|---|
| Molecular Weight(MW) | 74810 Da |
| Function | Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors |
| Tissue Specificity | Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (By similarity) Isoform 3: Secreted (Probable). Isoform 5: Secreted (Probable). |
| Entrez Gene | 132014 |
|---|---|
| Nucleotide Accession | NP_001180309.1 NP_705613.1 NP_705616.2 |
Application
IL17RE Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IL17RE antibody detected the IL17RE protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
