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IL21 Antibody (C-term)

Catalog Number:OM235861
OM235861
Discount Price
OM235861-100ul
1~2 Week
100ul
OM235861-50ul
50ul
OM235861-20ul
20ul
1~2 Week
Product Profile
Product Name IL21 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias IL21; Interleukin-21; Za11
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names IL21
Interleukin-21
Za11
Molecular Weight(MW) 17923 Da
Function Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation
Tissue Specificity Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes
Cellular Localization Secreted.
Database Links
Entrez Gene 59067
Nucleotide Accession NP_068575.1
Application

Application

IL21 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IL21 antibody detected the IL21 protein (arrow).

Application

Western blot analysis of IL21 (arrow) using rabbit polyclonal IL21 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IL21 gene.
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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