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ILKAP Antibody (Center)

Catalog Number:OM235922
OM235922
Discount Price
OM235922-100ul
1~2 Week
100ul
OM235922-50ul
50ul
OM235922-20ul
20ul
1~2 Week
Product Profile
Product Name ILKAP Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias ILKAP; Integrin-linked kinase-associated serine/threonine phosphatase 2C
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C
Molecular Weight(MW) 42907 Da
Function Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation
Tissue Specificity Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 80895
Nucleotide Accession NP_110395.1
Application

Application

ILKAP Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ILKAP antibody detected the ILKAP protein (arrow).

Application

ILKAP Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ILKAP antibody detected the ILKAP protein (arrow).

Application

ILKAP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of ILKAP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

Western blot analysis of ILKAP (arrow) using rabbit polyclonal ILKAP Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ILKAP gene.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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